Fast, flexible cell line development services

Comprehensive upstream process development capabilities, including cell line development, and a commitment to innovation, quality and service, make us the ideal partner for the process development of your mammalian cell culture projects. Our expertise spans multiple commercial cell lines, including CHO (Chinese Hamster Ovary), as well as cGMP cell banking.

Cell Line Development

Cell line development plays a major role in developing robust, cost-effective biologic processes.  Drug developers need rapid availability of high-performing mammalian cell lines for therapeutic protein production, and flexibility. With more than 30 years of process development experience, including more than 240 biologic development programs, we know how to transform your discovery into a drug substance. Establishing a sustainable process begins with cell line development that is built on speed, flexibility, and performance. Patheon, by Thermo Fisher Scientific, provides:

  • Simple cell line licensing agreements that avoid royalties or restrictions
  • Ability to work with a variety of mammalian cell lines and third-party cell line developers
  • Use of automation, Beacon and ambr® 15 platforms, to accelerate cell line development and optimize selection of top clone
  • Custom cell line development using the Thermo Fisher Gibco™ Freedom™ CHO-S™ kit and other cell lines
  • Experience with commercial cell lines: CHO, myeloma, hybridoma, and PER.C6®
  • Fast, flexible, complete solutions for FIH trials to support IND filing: Thermo Fisher Scientific Quick to Clinic™ program for biologics
  • Cell banking services

Flexible solutions are custom built from comprehensive technical capabilities in fed-batch and perfusion processes. Thermo Fisher Scientific also works with high-density mammalian cell culture technologies including our proprietary XD™ technology. Read about the Thermo Fisher Gibco™ Freedom™ CHO-S™ cell line.

Download our Quick to Clinic™ brochure for biologics.